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Abstract
This study evaluates different wavelengths of LED therapy in Wistar rats skin injuries. LEDs (Light Emitting Diodes) are phototherapeutic resource nowadays, since it is considered a good alternative to Low Level Laser Therapy in injury healing because of the lower cost. Twenty-five male Wistar rats were divided in five groups: Control, Red LED (630-780 nm), Green LED (490-565 nm), Blue LED (440-490 nm) and Yellow LED (590-630 nm). It´s a experimental research that it was performed during 4 weeks. Twenty-four hours after surgical injury (1cm²) was applied LED therapy for 6 minutes during five days. Red LED presented best anti-edematous effects in comparison to the other wavebands. The perimeters were reduced in all groups, but in Green and Red LED groups were significantly diminished (p<0,05) when compared to control and Blue LED groups. The best result of area was with Green LED and worst results with Blue LED. The use of non collimated phototherapy with Red, Green, Yellow and Blue LEDs improves the wounds healing process, mainly with Red wavelength. The non collimated phototherapy with LEDs could be included in Physiotherapy practice for wound healing improvement because of the lower cost in comparison with Low Level Laser Therapy and the benefits of irradiate a bigger area.
References
Leblanc S, Arabzadeh A, Benlolo S, Breton V, Turbide C, Beauchemin N, Nouvion AL. CEACAM1 deficiency delays important wound healing processes. Wound Repair Regen 2011; 19(6): 745-52. http://dx.doi.org/10.1111/j.1524-475X.2011.00742.x
Araújo EMM, Almeida CSC, Godinho Junior JMF, Nascimento FRF, Santos APSA. Ativação in vitro do sistema complemento como mecanismo imunomodulador induzido pelo mesocarpo de babaçu. Rev. Ciênc. Saúde, São Luís, 2013; 15(1): 05-10.
Renno ACM, Iwama AM, Shima P, Fernandes KR, Carvalho JG, Oliveira P, Ribeiro DA. Effect of low-level laser therapy (660 nm) on the healing of second-degree skin burns in rats. Journal of Cosmetic and Laser Therapy 2011; 13(5): 237-242. http://dx.doi.org/10.3109/14764172.2011.606466
Lau PS, Noriah B, Chong JC, Asmah H. Light-based therapy on wound healing : a review. Laser Phys 2014; 24(8): 3001
Sousa APC, Paraguassú GM, Silveira NTT, Souza J, Cangussú MCT, Santos JN, Pinheiro ALB. Laser and LED phototherapies on angiogenesis. Lasers Med Sci 2013; 28: 981-987. http://dx.doi.org/10.1007/s10103-012-1187-z
Barolet D. The importance of pulsing illumination parameters in LLLT. Proc. SPIE, Mechanisms for Low-Light Therapy 2010; 7552: 03.
Fahimipour F, Mahdian M, Houshmand B, Aasnaashari M, Sadrabadi AN, Farashah SEN, Mousavifard SM, Khojasteh A. The effect of He-Ne and Ga-Al-As laser light on the healing of hard palate mucosa of mice. Lasers Med Sci 2013; 28: 93-100. http://dx.doi.org/10.1007/s10103-012-1060-0
Ejiri K, Aoki A, Yamaguchi Y, Ohshima M, Izumi Y. High-frequency low-level diode laser irradiation promotes proliferation and migration of primary cultured human gingival epithelial cells. Lasers Med Sci 2014; 29: 1339-1347. http://dx.doi.org/10.1007/s10103-013-1292-7
Sebastian A, Syed F, Perry D, Balamurugan V, Colthurst J, Chaudhry IH, Bayat A. Acceleration of cutaneous healing by electrical stimulation: Degenerate electrical waveform down-regulates inflammation, up-regulates angiogenesis and advances remodeling in temporal punch biopsies in a human volunteer study. Wound Repair Regen 2011; 19(6): 693-708. http://dx.doi.org/10.1111/j.1524-475X.2011.00736.x
Yeh NG, Wu CH, Cheng TC. Light-emitting diodes — Their potential in biomedical applications. Renewable and Sustainable Energy Reviews 2010; 14: 2161-2166. http://dx.doi.org/10.1016/j.rser.2010.02.015
Sauder DN. Light-emitting diodes: their role in skin rejuvenation. International Journal of Dermatology 2010; 49(1): 12-16. http://dx.doi.org/10.1111/j.1365-4632.2009.04246.x
Carvalho PTC, Silva IS, Reis FA, Perreira DM, Aydos RD. Influence of ingaalp laser (660nm) on the healing of skin wounds in diabetic rats. Acta Cirúrgica Brasileira 2010; 25 (1): 71. http://dx.doi.org/10.1590/S0102-86502010000100016
Meyer PF, Araújo HG, CarvalhoBMGF, Tatum BIS, Fernandes ICAG, Ronzio OA, Pinto MVM. Assessment of effects of LED on skin wound healing in Wistar rats. Fisioterapia Brasil 2010; 11(6): 428-432.
Chaves MEA, Araújo AR, Piancastelli ACC, Pinot M. Effects of low-power light therapy on wound healing: LASER x LED. An Bras Dermatol 2014; 89(4): 616-23. http://dx.doi.org/10.1590/abd1806-4841.20142519
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Copyright (c) 2015 Hennes Gentil de Araujo, Rodrigo Marcel Valentim da Silva, Pablo Miranda Canela, Nayrane de Farias Silva, Fernando Claudino dos Santos-Filho, Oscar Ariel Ronzio, Maria Goretti Freire de Carvalho, Sebastião David Santos-Filho , Patrícia Froes Meyer