Relevance of Autonomic Arousal in the Stress Response in Psychopathology
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Keywords

 Psychophysiology, autonomic arousal, Behavioral Activation System (BAS), Behavioral Inhibition System (BIS), differential diagnosis, psychopathology.

How to Cite

C. Pruneti, M. Saccò, C. Cosentino, & D. Sgromo. (2016). Relevance of Autonomic Arousal in the Stress Response in Psychopathology. Journal of Basic & Applied Sciences, 12, 176–184. https://doi.org/10.6000/1927-5129.2016.12.26

Abstract

The principal goal of this study is to describe the relevance of typical autonomic patterns of response in accordance to a number of psychopathological syndromes for an accurate multi-dimensional assessment.
A sample of 89 subjects was subdivided in five pathological groups in accordance with the clinical diagnosis following the diagnostic criteria of DSM V [1]: Generalized Anxiety Disorder (GAD), Panic Attack Disorders (PAD), Major Depressive Episodes (MDE), Obsessive Compulsive Disorders (OCD), Anorexia Nervosa (AN) and a Healthy control group. Obtained data were compared in regard to each physiological parameters by using the mean value of the last minute of the registration at rest, and two activation indexes: “stress response” and “recovery after stress”.
Furthermore, for each of the physiological parameters (EMG, SCL/SCR, PT and HR), and diagnostic group, mean values in the three different phases (last minute of rest, first minute of stress, last minute of recovery) were compared to evaluate the four physiological parameters trends.
In GAD and PAD patients, the obtained Conductance Response mean values are much higher than MDE and OCD.
Furthermore, the HR response is also higher in GAD than in the other three groups. So, OCD and MDE patients seem to be characterized by a flat profile in all the parameters.
We confirmed that a condition of autonomic hyper activation is typically connected to a high level of tension and anxiety; vice versa, a low level of autonomic activation and the impossibility to react to the stimuli is typically connected to MDE, OCD and AN.Obtained data suggest that there might be a new tool for differential diagnosis in psychopathology, represented by specific and typical pattern in autonomic response.

https://doi.org/10.6000/1927-5129.2016.12.26
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References

American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders (DSM-5). Washington: American Psychiatric Publishing 2013.

Gray JA. The neuropsychology of anxiety. Br J Psychol 1978; 69: 417-38. http://dx.doi.org/10.1111/j.2044-8295.1978.tb02118.x

Fowles DC. The three arousal model: implications of Gray’s two-factor learning theory for heart rate, electrodermal activity, and psychopathy. Psychophysiol 1980; 17: 87-104. http://dx.doi.org/10.1111/j.1469-8986.1980.tb00117.x

Fowles DC. Psychophysiology and psychopathology: a motivational approach. Psychophysiol 1988; 25: 373-91. http://dx.doi.org/10.1111/j.1469-8986.1988.tb01873.x

Fuller GD. Biofeedback Methods and Procedures in Clinical Practice. S. Francisco: Biofeedback Press 1979.

Sanavio E, Bettinardi O. Parametri psicofisiologici e cognitivo-verbali: contributo alla validazione di un “profilo di stress”. Atti del V Congresso Nazionale di Biofeedback e Medicina Comportamentale; Padova: Liviana 1984; pp. 201-9.

Sanavio E. L’assessment psicofisiologico nella clinica comportamentale. Roma: Bulzoni 1985.

Zotti AM, Bettinardi O, Soffiantino F, Gavazzi L, Steptoe A. Psychophysiological stress testing in postinfarction patients. Psychological correlates of cardiovascular arousal and abnormal cardiac responses. Circulation 1991; 83(4Suppl): II25-35.

Pruneti C, Fontana F. Psicofisiologia clinica. Parma: Ed Libreria Medico Scientifica 2010.

Hoehn SR, McLeod DR, Zimmerli WD. Psychophysiological response patterns in panic disorder. Acta Psichiatr Scand 1991; 83 (1): 4-11. http://dx.doi.org/10.1111/j.1600-0447.1991.tb05503.x

Pruneti C. Presentazione e valutazione psicofisiologica di una versione computerizzata delle CPM di Raven. Bollettino di Psicologia Applicata 1995; 210: 41-47.

Stegagno L, Palomba D. Psicofisiologia clinica. In: Stegagno L, eds. Psicofisiologia. Vol. 2: correlati fisiologici dei processi cognitivi e del comportamento. Torino: Bollati Boringhieri 1994.

Pruneti C, Fontana F, Bicchieri L. Conduttanza cutanea come indice nella diagnosi differenziale in psicopatologia. Psicoterapia Cognitiva e Comportamentale 2006; 12(19): 203-6.

Crocetti A, Masaraki S, Merati S, Menotti R, Forti S, Aiello G. Psychophysiological stress profile: a protocol to differentiate normal vs pathological subjects. Biogenic Amines 2011; 25(1): 34-41.

Hoehn-Saric R. Physiologic responses in anxiety. Curr Psychiatry Rev 2007; 3(3): 196-204. http://dx.doi.org/10.2174/157340007781369667

Lader MH. The psychophysiology of anxious and depressed patients. In: Fowles DC, eds. Clinical applications of psychophysiology. New York: Columbia University Press 1975

Lader MH. Anxiety and depression. In: Gale A, Edwards JA, eds. Physiological correlates of human behavior. Londra: Academic Press 1983. http://dx.doi.org/10.1016/b978-0-12-273903-3.50015-8

Pruneti C, Petraglia F, Rossi F, Stomati M, Luisi M, Genazzani MR. Studio, in doppio cieco, degli effetti a livello comportamentale psicofisiologico ed endocrinologico in pazienti con amenorrea ipotalamica, di un trattamento farmacologico a breve termine con Pivagabina (PVG). Giornale Italiano di psicopatologia 1999; 5(1): 75-81.

Pruneti C, Giusti M, Boem A, Luisi M. Behavioral, psychophysiological and salivary cortisol after short term alprazolam treatment in patients with recent myocardial infarction. Ital Hearth J 2002; 3(1): 53-9.

Sanavio E, Bertolotti G, Michielin M, Vidotto G, Zotti AM. CBA 2.0. Cognitive Behavioural Assessment. Scale Primarie. Manuale. Firenze: Organizzazioni Speciali 1997.

Arena JG, Blanchard EB. Reliability of psychophysiological assessment. Behav Res Ther 1983; 21: 447-60. http://dx.doi.org/10.1016/0005-7967(83)90014-1

Rommel D, Nandrino JL, De Jonckheere J, Swierczek M, Dodin V, Logier R. Maintenance of parasympathetic inhibition following emotional induction in patients with restrictive anorexia nervosa. Psychiatry Res 2015; 225(3): 651-7. http://dx.doi.org/10.1016/j.psychres.2014.11.030

Wood KH, Ver Hoef LW, Knight DC. The amygdala mediates the emotional modulation of threat-elicited skin conductance response. Emotion 2014; 14(4): 693. http://dx.doi.org/10.1037/a0036636

Allan NP, Macatee RJ, Norr AM, Schmidt NB. Direct and interactive effects of distress tolerance and anxiety sensitivity on generalized anxiety and depression. Cognitive Therapy and Research 2014; 38(5): 530-540. http://dx.doi.org/10.1007/s10608-014-9623-y

Wilhem F, Trabert W, Roth WT. Physiologic instability in Panic Disorder and Generalized Axiety Disorder. Biol Psychiatry 2001; 49: 596-605. http://dx.doi.org/10.1016/S0006-3223(00)01000-3

Wood CM, Cano-Vindel A, Salguero JM, Wood CM. A multi-factor model of panic disorder: Results of a preliminary study integrating the role of perfectionism, stress, physiological anxiety and anxiety sensitivity. Anales de Psicologia 2015; 31(2): 481-487. http://dx.doi.org/10.6018/analesps.31.2.184241

Tchanturia K, Liao PC, Uher R, Lawrence N, Treasure J, Campbell IC. An investigation of decision making in anorexia nervosa using the Iowa Gambling Task and skin conductance measurements. J Int Neuropsych Soc 2015; 13: 635-641. http://dx.doi.org/10.1017/s1355617707070798

Seligman MEP, Abramson LV, Semmel A, Von Beyer C. Depressive attributional style. J Abnorm Psychol 1979; 88: 242-7. http://dx.doi.org/10.1037/0021-843X.88.3.242

Schwerdtfeger A, Rosenkaimer AK. Depressive symptoms and attenuated physiological reactivity to laboratory stressors. Biolo Psychol 2011; 87(3): 430-8. http://dx.doi.org/10.1016/j.biopsycho.2011.05.009

Landgraf D, Long J, Der-Avakian A, Streets M, Welsh DK. Dissociation of Learned Helplessness and Fear Conditioning in Mice: A Mouse Model of Depression. PLoS ONE 2015; 10(4): e0125892. http://dx.doi.org/10.1371/journal.pone.0125892

Bosmans G, Poiana N, Van Leeuwen K, Dujardin A, De Winter S, Finet C, Van de Walle M. Attachment and depressive symptoms in middle childhood The moderating role of skin conductance level variability. Journal of Social and Personal Relationships 2015; 0265407515618278. http://dx.doi.org/10.1177/0265407515618278

Pruneti C, Rota S, Rossi S. Profilo psicofisiologico di pazienti con prevalenti sintomi ansiosi e depressivi con e senza trattamento farmacologico. Psicoterapia Cognitiva e Comportamentale 2000; 6(3): 255-65.

Hohen S, McLeod DR, Hipsley P. Is hyperarousal essential to obsessive-compulsive disorder? Diminished physiologic flexibility, but not hyperarousal, characterizes patients with obsessive-compulsive disorder. Arch Gen Psychiatry 1995; 52(8): 688-93. http://dx.doi.org/10.1001/archpsyc.1995.03950200078017

Dractu L, Bond A. Panic patients in the non-panic state: physiological and cognitive dysfunction. Eur Psychiatry 1998; 13: 18-25. http://dx.doi.org/10.1016/S0924-9338(97)86747-8

Roth WT, Wilhem FH, Trabert W. Autonomic instability during relaxation in panic disorder. Psychiatry Res 1998; 80: 155-64. http://dx.doi.org/10.1016/S0165-1781(98)00066-3

Parente AC, Garcia-Leal C, Del-Ben CM, Guimarães FS, Graeff FG. Subjective and neurovegetative changes in healthy volunteers and panic patients performing simulated public speaking. Eur Neuropsyhopharmacol 2005; 15(6): 663-71. http://dx.doi.org/10.1016/j.euroneuro.2005.05.002

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Copyright (c) 2016 C. Pruneti, M. Saccò, C. Cosentino , D. Sgromo