Keywords
Bacopa monniera
neurotransmitter
acetyl choline
reactive oxidative specie
How to Cite
Abstract
The aim of this study was to compare the effect of selected drugs, Intellan and cyanocobalamin on some aspects of animal behavior, like effect on memory, depression, gross behavior and exploratory activity. Results of present investigations reveals cyanocobalamin to be a good memory enhancer and intellan also showed memory boosting effects in addition to anti-anxiety activity which affects overall performance.
References
Bhattacharya, A., Chatterjee, A., Ghosal, S., Bhattacharya, S.K., 1999. Antioxidant activity of tannoid principles of emblica officinalis (amla). Ind . J. Exp. Biol. 37, 676-680.
Das, A., Shanker, G., Nath, C., Pal, R., Singh, S., Singh, H., 2002. A comparative study in rodents of standardized extracts of Bacopa monniera and Ginkgo biloba: Anti cholinesterase and cognitive enhancing activities. Pharmacology, Biochemistry and Behavior 73, 893–900.
Kishore, K., Singh, M., 2005. Effect of bacosides, alcoholic extract of Bacopa monniera Linn. (Brahmi), on experimental amnesia in mice. Indian Journal of Experimental Biology 43, 640–645.
D’Esposito, M., Postle, B.R., Ballard, D., Lease, J., 1999. Maintenance versus manipulation of information held inworking memory: an event-related fMRI study. Brain Cognition 41, 66–86.
Smith, E.E., Jonides, J., 1999. Storage and executive processes in the frontal lobes. Science 283, 16571–1661.
Moser, M.B., Moser, E.I., 1998 . Distributed encoding and retrieval of spatial memory in the hippocampus. The Journal of Neuroscience 18, 7535–7542.
Goldman-Rakic, P.S. , Muly III, E.C., Williams, G.V., 2000. D1 receptors in prefrontal cells and circuits. Brain Research Reviews 31, 295–301.
Arnsten, A.F.T., Robbins, T.W., 2002. Neurochemical modulation of prefrontal function in humans and animals. In: Stuss, D.T., Knight, R.T. (Eds.), Principles of Frontal Lobe Function. Oxford University Press, New york.
Stancampiano, R., Cocco, S., Cugusi, C., Sarais, L., Fadda, F., 1999. Serotonin and acetylcholine release response in the rat hippocampus during a spatial memory task. Neuroscience 89, 1135–1143.
Sara S.J., 1989. Noradrenergic-cholinergic interaction: its possible role in memory dysfunction associated with senile dementia. Arch. Gerontol.Geriatr. 1S, 99-108.
Singh H.K., Dhawan B.N., 1997. Neuropsychopharmacological effects of Ayurvedic nootropic Bacopa monniera Linn (Brahmi). Indian J.Pharmachol. 29, S359-S365.
Subathra M, Shila S, Devi M.A., Panneerselvam C, 2005. Emerging role of Centella asiatica in improving age related neurological antioxidant status.Exp Gerontol; 40(8-9):707- 715.
Teruhiko Koike, Masafumi Kuzuya, Shigeru Kanda, Kiwako Okada, Sachiko Izawa, Hiromi Enoki, Akihisa Iguchi 2008. Raised homocysteine and low folate and vitamin B-12 concentrations predict cognitive decline in communitydwelling older Japanese adults .Clinical Nutrition, Volume 27, Issue 6, December 2008, Pages 865-871.
Newbold H.L., 1988. VitaminB12–megaloblastic madness and the founding of Duke University. Medical hypothesis volume 27, issue 3, Nov, 1988, 231-240.
Maike Walters,Alexander Ströhle,Andreas Hahn 2004. Cobalamine a critical vitamin in elderly .Preventive medicine ,vol 39,issue 6 Dec 2004.1256-1266
Saillenfait AM, Vannier B. 1988. Methodological proposal in behavioral teratogenicity testing: assessment of propoxyphene, chlorpromazine, and vitamin A as positive controls. Teratology 37: 185-99
Durcan MJ, Lister RG.Time course of ethanol effects on locomotor activity, exploration and anxiety in mice. Psychol Pharmacol 1988; 96: 67-72
Porsolt RD, Le Pichon M, Jalfre M 1977. Depression :A new animal model sensitive to antidepressant treatments,Nature 266: 730-732
Porsolt RD, Anton G, Blavet N, Jalfre M 1978. Behavioral despair in rats: A new model for screening antidepressant in mice. Psychopharmacology Biol Psychiatry 11:659-671
Alcaraz MJ.,Jimenez MJ.1989. Journal of natural products.52 (5) 1088-1091.
Sulochana B.Rao ,M.Chetana ,P .Uma Devi, 2005. Centella asiatica treatment during postnatal period enhances learning and memory in mice. Physiology and Behavior,vol 86, Pages 449-457
Chatterjee TK, Chakraborty A, Pathak M. Effect of plant extract centella asiatica (linn) on cold restraint stress ulcer in rats.Indian J. Exp Biol.1992;889-891
Emamgoreishi M, Khasaki M, Aazam MF. 2005 Coriander sativum evaluation of its anxiolytic effect in elevated plus maize.Journal of Ethanopharmacology 96 (3) 365-370.
Servet Ariogul, Mustafa Cankunatan, Neslihann Degali, Meltem Khalil, Bureu Yavuz 2005. Archieves of gerontology and geriatrics, vol 40, Issue 2, 139-146.
Nanteetip Limpeanchob, Somkiet Jaipan, Saisunee Rattanakaruna, Watoo Phrompittayarat, Kornkanok Ingkaninan 2008. Neuroprotective effect of Bacopa monnieri on beta-amyloid-induced cell death in primary cortical culture Journal of ethnopharmacology, Vol 120, Issue1, Pages 112- 117.
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